ATR‐dependent ubiquitin‐specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance

ATR‐dependent ubiquitin‐specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance

Abstract Oxaliplatin (OXA) resistance is a major clinic challenge in hepatocellular carcinoma (HCC). Ferroptosis is a kind of iron‐dependent cell death. Triggering ferroptosis is considered to restore sensitivity to chemotherapy. In the present study, we found that USP20 was overexpressed in OXA‐res...

Full description

Bibliographic Details
Main Authors: Jianing Tang, Guo Long, Desheng Xiao, Shuang Liu, Liang Xiao, Ledu Zhou, Yongguang Tao
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:MedComm
Subjects:
chemoresistance
ferroptosis
hepatocellular carcinoma
solute carrier family 7 member 11
ubiquitin‐specific peptidase 20
Online Access:https://doi.org/10.1002/mco2.463

Internet

https://doi.org/10.1002/mco2.463

Similar Items