Aberrant Dyskerin Expression Is Related to Proliferation and Poor Survival in Endometrial Cancer

Aberrant Dyskerin Expression Is Related to Proliferation and Poor Survival in Endometrial Cancer

Dyskerin is a core-component of the telomerase holo-enzyme, which elongates telomeres. Telomerase is involved in endometrial epithelial cell proliferation. Most endometrial cancers (ECs) have high telomerase activity; however, dyskerin expression in human healthy endometrium or in endometrial pathol...

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Bibliographic Details
Main Authors: Rafah Alnafakh, Gabriele Saretzki, Angela Midgley, James Flynn, Areege M. Kamal, Lucy Dobson, Purushothaman Natarajan, Helen Stringfellow, Pierre Martin-Hirsch, Shandya B. DeCruze, Sarah E. Coupland, Dharani K. Hapangama
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
dyskerin
<i>DKC1</i>
endometrial cancer
telomerase
proliferation
telomeres
Online Access:https://www.mdpi.com/2072-6694/13/2/273

Internet

https://www.mdpi.com/2072-6694/13/2/273

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