Precise spatial and temporal control of oxygen within in vitro brain slices via microfluidic gas channels.

The acute brain slice preparation is an excellent model for studying the details of how neurons and neuronal tissue respond to a variety of different physiological conditions. But open slice chambers ideal for electrophysiological and imaging access have not allowed the precise spatiotemporal contro...

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Bibliographic Details
Main Authors: Gerardo Mauleon, Christopher P Fall, David T Eddington
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3419219?pdf=render