Low Dose Interleukin-2 Ameliorates Sjögren’s Syndrome in a Murine Model

Low Dose Interleukin-2 Ameliorates Sjögren’s Syndrome in a Murine Model

Sjögren’s syndrome (SS) is a systemic autoimmune disease with no efficient treatment, and it is associated with dysregulated immune cells and impaired interleukin (IL)-2 signaling. IL-2 is critical for the development and maintenance of Treg cells. The use of low dose of IL-2 (LDIL-2) in the treatme...

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Bibliographic Details
Main Authors: Yifan Wang, Ruiling Feng, Gong Cheng, Bo Huang, Jiayi Tian, Yuzhou Gan, Yuebo Jin, Miao Miao, Xia Zhang, Xiaolin Sun, Jing He, Zhanguo Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Medicine
Subjects:
Sjögren’s syndrome
interleukin-2
NOD mice
Treg cell
Tfh cells
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.887354/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.887354/full

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