Erk1/2-Dependent HNSCC Cell Susceptibility to Erastin-Induced Ferroptosis

Erk1/2-Dependent HNSCC Cell Susceptibility to Erastin-Induced Ferroptosis

Unfavorable clinical outcomes mean that cancer researchers must attempt to develop novel therapeutic strategies to overcome therapeutic resistance in patients with HNSCC. Recently, ferroptosis was shown to be a promising pathway possessing druggable targets, such as xCT (SLC7A11). Unfortunately, lit...

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Bibliographic Details
Main Authors: Dragana Savic, Teresa Bernadette Steinbichler, Julia Ingruber, Giulia Negro, Bertram Aschenbrenner, Herbert Riechelmann, Ute Ganswindt, Sergej Skvortsov, József Dudás, Ira-Ida Skvortsova
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
HNSCC
erastin
xCT
ERK signaling
Online Access:https://www.mdpi.com/2073-4409/12/2/336

Internet

https://www.mdpi.com/2073-4409/12/2/336

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