Frequencies of CYP2D6 genetic polymorphisms in Arab populations

Frequencies of CYP2D6 genetic polymorphisms in Arab populations

Abstract CYP2D6 is a key drug-metabolizing enzyme implicated in the biotransformation of approximately 25% of currently prescribed drugs. Interindividual and interethnic differences in CYP2D6 enzymatic activity, and hence variability in substrate drug efficacy and safety, are attributed to a highly...

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Bibliographic Details
Main Authors: Mousa Alali, Wouroud Ismail Al-khalil, Sara Rijjal, Lana Al-Salhi, Maher Saifo, Lama A. Youssef
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Human Genomics
Subjects:
CYP2D6
Duplications
Allele frequency
Single nucleotide polymorphisms
Genotype
Arabs
Online Access:https://doi.org/10.1186/s40246-022-00378-z

Internet

https://doi.org/10.1186/s40246-022-00378-z

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