Investigation of Receptor Heteromers Using NanoBRET Ligand Binding

Investigation of Receptor Heteromers Using NanoBRET Ligand Binding

Receptor heteromerization is the formation of a complex involving at least two different receptors with pharmacology that is distinct from that exhibited by its constituent receptor units. Detection of these complexes and monitoring their pharmacology is crucial for understanding how receptors funct...

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Bibliographic Details
Main Authors: Elizabeth K. M. Johnstone, Heng B. See, Rekhati S. Abhayawardana, Angela Song, K. Johan Rosengren, Stephen J. Hill, Kevin D. G. Pfleger
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
NanoBRET
Nluc
GPCR
heteromer
ligand binding
Receptor-HIT
Online Access:https://www.mdpi.com/1422-0067/22/3/1082

Internet

https://www.mdpi.com/1422-0067/22/3/1082

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