Friedländer-Type Reaction of 4-Cholesten-3-one with 2′-Aminoacetophenone: Angular versus Linear Quinoline-Fused Steroids

Friedländer-Type Reaction of 4-Cholesten-3-one with 2′-Aminoacetophenone: Angular versus Linear Quinoline-Fused Steroids

To optimize the experimental conditions used for the Friedländer-type condensation, an angular fused 4-substituted quinoline steroid has been obtained in very high yield and regioselectivity using readily available 4-cholesten-3-one and 2′-aminoacetophenone. Moreover, by varying the reaction conditi...

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Bibliographic Details
Main Authors: Caterina Momoli, Valerio Morlacci, Marco Chiarini, Laura Palombi, Antonio Arcadi
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molbank
Subjects:
fused steroid quinoline polycycles
Friedlӓnder’s condensation
angular cholestanoquinoline
linear cholestanoquinoline
Online Access:https://www.mdpi.com/1422-8599/2023/3/M1712

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https://www.mdpi.com/1422-8599/2023/3/M1712

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