γδ T cells control humoral immune response by inducing T follicular helper cell differentiation

γδ T cells control humoral immune response by inducing T follicular helper cell differentiation

Many immune functions have been reported for γδ T cells, including the regulation of antibody responses. Here the authors show that CXCR5+ γδ T cells release Wnt ligands to initiate the T follicular helper cell differentiation program and promote antibody production.

Bibliographic Details
Main Authors: Rafael M. Rezende, Amanda J. Lanser, Stephen Rubino, Chantal Kuhn, Nathaniel Skillin, Thais G. Moreira, Shirong Liu, Galina Gabriely, Bruna A. David, Gustavo B. Menezes, Howard L. Weiner
Format: Article
Language:English
Published: Nature Portfolio 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05487-9

Internet

https://doi.org/10.1038/s41467-018-05487-9

Similar Items