Digital quantitative tissue image analysis of hypoxia in resected pancreatic ductal adenocarcinomas

Digital quantitative tissue image analysis of hypoxia in resected pancreatic ductal adenocarcinomas

BackgroundTumor hypoxia is theorized to contribute to the aggressive biology of pancreatic ductal adenocarcinoma (PDAC). We previously reported that hypoxia correlated with rapid tumor growth and metastasis in patient-derived xenografts. Anticipating a prognostic relevance of hypoxia in patient tumo...

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Bibliographic Details
Main Authors: Iram Siddiqui, Jade Bilkey, Trevor D. McKee, Stefano Serra, Melania Pintilie, Trevor Do, Jing Xu, Ming-Sound Tsao, Steve Gallinger, Richard P. Hill, David W. Hedley, Neesha C. Dhani
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
hypoxia
tumor microenvironment
ductal adenocarcinoma (PDAC)
tumor heterogeneity
image analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.926497/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.926497/full

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