Protein Succinylation and Malonylation as Potential Biomarkers in Schizophrenia

Protein Succinylation and Malonylation as Potential Biomarkers in Schizophrenia

Two protein post-translational modifications, lysine succinylation and malonylation, are implicated in protein regulation, glycolysis, and energy metabolism. The precursors of these modifications, succinyl-CoA and malonyl-CoA, are key players in central metabolic processes. Both modification profile...

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Bibliographic Details
Main Authors: Bradley Joseph Smith, Caroline Brandão-Teles, Giuliana S. Zuccoli, Guilherme Reis-de-Oliveira, Mariana Fioramonte, Verônica M. Saia-Cereda, Daniel Martins-de-Souza
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Journal of Personalized Medicine
Subjects:
succinylation
malonylation
schizophrenia
antipsychotics
biomarkers
post-translational modifications
Online Access:https://www.mdpi.com/2075-4426/12/9/1408

Internet

https://www.mdpi.com/2075-4426/12/9/1408

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