Microglia TREM1-mediated neuroinflammation contributes to central sensitization via the NF-κB pathway in a chronic migraine model

Microglia TREM1-mediated neuroinflammation contributes to central sensitization via the NF-κB pathway in a chronic migraine model

Abstract Background Neuroinflammation, mediated by the activation of microglia, contributes to central sensitization, which is associated with the development of chronic migraine (CM). TREM1 receptors amplify the inflammatory response. However, their relationship to CM is unclear. Thus, this study e...

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Bibliographic Details
Main Authors: Songtang Sun, Zhenzhen Fan, Xuejiao Liu, Longde Wang, Zhaoming Ge
Format: Article
Language:English
Published: BMC 2024-01-01
Series:The Journal of Headache and Pain
Subjects:
TREM1
Microglia
Chronic migraine
NF-κB
Central sensitization
Online Access:https://doi.org/10.1186/s10194-023-01707-w

Internet

https://doi.org/10.1186/s10194-023-01707-w

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