Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression

Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression

Unrecognized depression during adolescence can result in adult suicidal behaviour. The aim of this study was to identify, replicate and characterize DNA methylation (DNAm) shifts in depression aetiology, using a longitudinal, multi-tissue (blood and brain) and multi-layered (genetics, epigenetics, t...

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Bibliographic Details
Main Authors: Diana M. Ciuculete, Sarah Voisin, Lara Kular, Nipuni Welihinda, Jörgen Jonsson, Maja Jagodic, Jessica Mwinyi, Helgi B. Schiöth
Format: Article
Language:English
Published: Taylor & Francis Group 2020-07-01
Series:Epigenetics
Subjects:
adolescent depression
hgf/c-met signalling
dna methylation
epigenetics
epigenome-wide analysis
Online Access:http://dx.doi.org/10.1080/15592294.2019.1700628

Internet

http://dx.doi.org/10.1080/15592294.2019.1700628

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