MAGI1 localizes to mature focal adhesion and modulates endothelial cell adhesion, migration and angiogenesis

MAGI1 localizes to mature focal adhesion and modulates endothelial cell adhesion, migration and angiogenesis

MAGI1 is an intracellular adaptor protein that stabilizes cell junctions and regulates epithelial and endothelial integrity. Here, we report that that in endothelial cells MAGI1 colocalizes with paxillin, β3-integrin, talin 1, tensin 3 and α-4-actinin at mature focal adhesions and actin stress fiber...

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Bibliographic Details
Main Authors: Begoña Alday-Parejo, Kedar Ghimire, Oriana Coquoz, Gioele W. Albisetti, Luca Tamò, Jelena Zaric, Jimmy Stalin, Curzio Rüegg
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Cell Adhesion & Migration
Subjects:
cell adhesion
migration
signaling
extracellular matrix
cytoskeleton
stress fibers
Online Access:http://dx.doi.org/10.1080/19336918.2021.1911472

Internet

http://dx.doi.org/10.1080/19336918.2021.1911472

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