Identification of prognostic values defined by copy number variation, mRNA and protein expression of LANCL2 and EGFR in glioblastoma patients

Identification of prognostic values defined by copy number variation, mRNA and protein expression of LANCL2 and EGFR in glioblastoma patients

Abstract Background Epidermal growth factor receptor (EGFR) and lanthionine synthetase C-like 2 (LanCL2) genes locate in the same amplicon, and co-amplification of EGFR and LANCL2 is frequent in glioblastoma. However, the prognostic value of LANCL2 and EGFR co-amplification, and their mRNA and prote...

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Bibliographic Details
Main Authors: Hua-fu Zhao, Xiu-ming Zhou, Jing Wang, Fan-fan Chen, Chang-peng Wu, Peng-yu Diao, Lin-rong Cai, Lei Chen, Yan-wen Xu, Jing Liu, Zong-yang Li, Wen-lan Liu, Zhong-ping Chen, Guo-dong Huang, Wei-ping Li
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Translational Medicine
Subjects:
Glioblastoma
LANCL2
EGFR
Overall survival
Amplification
Overexpression
Online Access:https://doi.org/10.1186/s12967-021-02979-z

Internet

https://doi.org/10.1186/s12967-021-02979-z

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