Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno‐Associated Viral Vector rAAV9P1

Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno‐Associated Viral Vector rAAV9P1

Abstract Astrocytes have crucial functions in the central nervous system (CNS) and are major players in many CNS diseases. Research on astrocyte‐centered diseases requires efficient and well‐characterized gene transfer vectors. Vectors derived from the Adeno‐associated virus serotype 9 (AAV9) target...

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Bibliographic Details
Main Authors: Amelie Bauer, Matteo Puglisi, Dennis Nagl, Joel A Schick, Thomas Werner, Andreas Klingl, Jihad El Andari, Veit Hornung, Horst Kessler, Magdalena Götz, Dirk Grimm, Ruth Brack‐Werner
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Advanced Science
Subjects:
AAV
Adeno‐associated virus
astrocytes
integrins
receptor profile
vectors
Online Access:https://doi.org/10.1002/advs.202104979

Internet

https://doi.org/10.1002/advs.202104979

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