Targeting AQP9 enhanced the anti-TNF therapy response in Crohn's disease by inhibiting LPA-hippo pathway
Although anti-TNF antibodies are extensively used to treat Crohn's disease (CD), a significant proportion of patients, up to 40%, exhibit an inadequate response to this therapy. Our objective was to identify potential targets that could improve the effectiveness of anti-TNF therapy in CD. Throu...
Main Authors: | Minhao Yu, Yuan Shi, Yuan Gao, Yang Luo, Yihua Jin, Xiaoyi Liang, Zhuoran Tao, Guojun Zhu, Haiping Lin, Hao Li, Jun Qin, Zhijun Cao, Ming Zhong |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-05-01
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Series: | Pharmacological Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1043661824001166 |
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