Tertiary Lymphatic Structures in Primary Hepatic Carcinoma: Controversy Cannot Overshadow Hope

Tertiary Lymphatic Structures in Primary Hepatic Carcinoma: Controversy Cannot Overshadow Hope

Tertiary lymphoid structures (TLSs) are organized aggregates of immune cells found in the tumor microenvironment. TLS can influence primary hepatic carcinoma (PHC) occurrence and have an active role in cancer. TLS can promote or inhibit the growth of PHC depending on their location, and although ava...

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Bibliographic Details
Main Authors: Weili Jia, Tianchen Zhang, Qianyun Yao, Jianhui Li, Ye Nie, Xinjun Lei, Zhenzhen Mao, Yanfang Wang, Wen Shi, Wenjie Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
tertiary lymphoid structures (TLS)
tumor-infiltrating lymphocytes (TIL)
primary hepatic carcinoma (PHC)
immunotherapy
cancer prognosis
immune microenvironment (IME)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.870458/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.870458/full

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