Recent Advances on Small-Molecule Antagonists Targeting TLR7

Toll-like receptor 7 (TLR7) is a class of pattern recognition receptors (PRRs) recognizing the pathogen-associated elements and damage and as such is a major player in the innate immune system. TLR7 triggers the release of pro-inflammatory cytokines or type-I interferons (IFN), which is essential fo...

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Bibliographic Details
Main Authors: Haoyang Zheng, Peiyang Wu, Pierre-Antoine Bonnet
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/2/634