Gut Microbiota Modulates the Protective Role of Ginsenoside Compound K Against Sodium Valproate-Induced Hepatotoxicity in Rat

Gut Microbiota Modulates the Protective Role of Ginsenoside Compound K Against Sodium Valproate-Induced Hepatotoxicity in Rat

This study aimed to investigate the potential role of gut microbiota in the hepatotoxicity of sodium valproate (SVP) and the protective effect of ginsenoside compound K (G-CK) administration against SVP-induced hepatotoxicity in rats. Measurements of 16S rRNA showed that SVP supplementation led to a...

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Bibliographic Details
Main Authors: Luping Zhou, Xiangchang Zeng, Jianwei Liao, Lulu Chen, Dongsheng Ouyang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Microbiology
Subjects:
sodium valproate
ginsenoside compound K
hepatotoxicity
gut microbiota
Akkermansia muciniphila
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.936585/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.936585/full

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