Circulating fibroblast activation protein α is reduced in acute ischemic stroke

BackgroundFibroblast activation protein α (FAP), a membrane glycoprotein with dipeptidyl-peptidase and collagenase properties, is expressed in atherosclerotic plaques and remodeling of the extracellular matrix based on fibrosis. Fibrosis is a main contributor of atrial cardiomyopathies. In acute MI,...

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Bibliographic Details
Main Authors: Jan-Thorben Sieweke, Gerrit M. Grosse, Karin Weissenborn, Anselm A. Derda, Saskia Biber, Johann Bauersachs, Udo Bavendiek, Jochen Tillmanns
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1064157/full