Bioactive compound C498-0670 alleviates LPS-induced sepsis via JAK/STAT and NFκB signaling pathways

Bioactive compound C498-0670 alleviates LPS-induced sepsis via JAK/STAT and NFκB signaling pathways

The JAK/STAT and NFκB signaling pathways are two major inflammatory signaling pathways that are usually activated simultaneously in the body’s inflammatory response to bacterial or viral infections. Hyperactivation of these two prominent signaling pathways is associated with various immune-related d...

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Bibliographic Details
Main Authors: Jing Xu, Xinxin Zhang, Mingming Zhou, Peizhe Lu, Yuting Xu, Lihong Wu, Qianyue Zhang, Zhihua Wu, Xiaoyu Xu, Pengfei Shi, Qingda Wei, Xiaoyu Li, Qiaoling Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
anti-inflammatory
JAK/STAT
NFκB
LPS
transcriptome sequencing
septic shock
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1132265/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1132265/full

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