Gp130-dependent release of acute phase proteins is linked to the activation of innate immune signaling pathways.

Gp130-dependent release of acute phase proteins is linked to the activation of innate immune signaling pathways.

Elevated levels of acute phase proteins (APP) are often found in patients with cardiovascular diseases. In a previous study, we demonstrated the importance of the IL-6-gp130 axis -as a key regulator of inflammatory acute phase signaling in hepatocytes-for the development of atherosclerosis.Gp130-dep...

Full description

Bibliographic Details
Main Authors: Maren Luchtefeld, Christoph Preuss, Frank Rühle, Eskindir P Bogalle, Anika Sietmann, Stefanie Figura, Werner Müller, Karsten Grote, Bernhard Schieffer, Monika Stoll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3087798?pdf=render

Internet

http://europepmc.org/articles/PMC3087798?pdf=render

Similar Items