Methyltransferase Dot1L promotes myogenic differentiation of skeletal muscle by regulating promoter methylation level

Objective To confirm whether methyltransferase Dot1L is involved in the regulation of myogenic differentiation, and explore its molecular mechanism in the regulation process. Methods Myoblast differentiation model of mouse C2C12 cell line was used to induce myogenic differentiation for 0, 1, 3 and...

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Bibliographic Details
Main Authors: LI Chengcheng, ZHOU Yong, LI Haoke, DENG Zhongliang
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2022-06-01
Series:陆军军医大学学报
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202111134.htm