Light chain 2 is a Tctex-type related axonemal dynein light chain that regulates directional ciliary motility in Trypanosoma brucei.

Flagellar motility is essential for the cell morphology, viability, and virulence of pathogenic kinetoplastids. Trypanosoma brucei flagella beat with a bending wave that propagates from the flagellum's tip to its base, rather than base-to-tip as in other eukaryotes. Thousands of dynein motor pr...

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Bibliographic Details
Main Authors: Subash Godar, James Oristian, Valerie Hinsch, Katherine Wentworth, Ethan Lopez, Parastoo Amlashi, Gerald Enverso, Samantha Markley, Joshua Daniel Alper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009984