The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity

The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity

Considerable evidence has been gathered over the last 10 years showing that the tumor microenvironment (TME) is not simply a passive recipient of immune cells, but an active participant in the establishment of immunosuppressive conditions. It is now well documented that hypoxia, within the TME, affe...

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Bibliographic Details
Main Authors: Joanna eBaginska, Elodie eViry, Jérôme ePaggetti, Sandrine eMedves, Guy eBerchem, Etienne eMoussay, Bassam eJanji
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Autophagy
Tumor Microenvironment
hypoxia
Natural Killer cells
tumor-derived exosomes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00490/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00490/full

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