Plasmodium berghei liver stage parasites exploit host GABARAP proteins for TFEB activation

Abstract Plasmodium, the causative agent of malaria, infects hepatocytes prior to establishing a symptomatic blood stage infection. During this liver stage development, parasites reside in a parasitophorous vacuole (PV), whose membrane acts as the critical interface between the parasite and the host...

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Bibliographic Details
Main Authors: Jacqueline Schmuckli-Maurer, Annina F. Bindschedler, Rahel Wacker, Oliver M. Würgler, Ruth Rehmann, Timothy Lehmberg, Leon O. Murphy, Thanh N. Nguyen, Michael Lazarou, Jlenia Monfregola, Andrea Ballabio, Volker T. Heussler
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07242-x