Mammalian Target of Rapamycin (mTOR) Signaling at the Crossroad of Muscle Fiber Fate in Sarcopenia

Mammalian Target of Rapamycin (mTOR) Signaling at the Crossroad of Muscle Fiber Fate in Sarcopenia

The mammalian target of rapamycin (mTOR) is a major regulator of skeletal myocyte viability. The signaling pathways triggered by mTOR vary according to the type of endogenous and exogenous factors (e.g., redox balance, nutrient availability, physical activity) as well as organismal age. Here, we pro...

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Bibliographic Details
Main Authors: Giuseppe Sirago, Anna Picca, Riccardo Calvani, Hélio José Coelho-Júnior, Emanuele Marzetti
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
aging
skeletal muscle
autophagy
mitophagy
protein synthesis
protein degradation
Online Access:https://www.mdpi.com/1422-0067/23/22/13823

Internet

https://www.mdpi.com/1422-0067/23/22/13823

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