MicroRNAs recruit eIF4E2 to repress translation of target mRNAs
Abstract MicroRNAs (miRNAs) recruit the RNA-induced silencing complex (RISC) to repress the translation of target mRNAs. While the 5′ 7-methylguanosine cap of target mRNAs has been well known to be important for miRNA repression, the underlying mechanism is not clear. Here we show that TNRC6A intera...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2017-07-01
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Series: | Protein & Cell |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1007/s13238-017-0444-0 |