Preclinical Evaluation of [<sup>18</sup>F]FACH in Healthy Mice and Piglets: An <sup>18</sup>F-Labeled Ligand for Imaging of Monocarboxylate Transporters with PET

Preclinical Evaluation of [<sup>18</sup>F]FACH in Healthy Mice and Piglets: An <sup>18</sup>F-Labeled Ligand for Imaging of Monocarboxylate Transporters with PET

The expression of monocarboxylate transporters (MCTs) is linked to pathophysiological changes in diseases, including cancer, such that MCTs could potentially serve as diagnostic markers or therapeutic targets. We recently developed [<sup>18</sup>F]FACH as a radiotracer for non-invasive m...

Full description

Bibliographic Details
Main Authors: Daniel Gündel, Masoud Sadeghzadeh, Winnie Deuther-Conrad, Barbara Wenzel, Paul Cumming, Magali Toussaint, Friedrich-Alexander Ludwig, Rareş-Petru Moldovan, Mathias Kranz, Rodrigo Teodoro, Bernhard Sattler, Osama Sabri, Peter Brust
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
monocarboxylate transporters (MCTs)
[<sup>18</sup>F]FACH
PET imaging
cancer
metabolism
kidney
Online Access:https://www.mdpi.com/1422-0067/22/4/1645

Internet

https://www.mdpi.com/1422-0067/22/4/1645

Similar Items