Upgrading SELEX Technology by Using Lambda Exonuclease Digestion for Single-Stranded DNA Generation

Upgrading SELEX Technology by Using Lambda Exonuclease Digestion for Single-Stranded DNA Generation

The generation of single-stranded DNA (ssDNA) molecules plays a key role in the SELEX (Systematic Evolution of Ligands by EXponential enrichment) combinatorial chemistry process and numerous molecular biology techniques and applications, such as DNA sequencing, single-nucleotide polymorphism (SNP) a...

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Bibliographic Details
Main Authors: Meltem Avci-Adali, Angel Paul, Nadj Wilhelm, Gerhard Ziemer, Hans Peter Wendel
Format: Article
Language:English
Published: MDPI AG 2009-12-01
Series:Molecules
Subjects:
aptamers
strand separation
streptavidin-coated beads
lambda exonuclease
single-stranded DNA
Online Access:http://www.mdpi.com/1420-3049/15/1/1/

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http://www.mdpi.com/1420-3049/15/1/1/

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