Long-Term Synaptic Plasticity Tunes the Gain of Information Channels through the Cerebellum Granular Layer

Long-Term Synaptic Plasticity Tunes the Gain of Information Channels through the Cerebellum Granular Layer

A central hypothesis on brain functioning is that long-term potentiation (LTP) and depression (LTD) regulate the signals transfer function by modifying the efficacy of synaptic transmission. In the cerebellum, granule cells have been shown to control the gain of signals transmitted through the mossy...

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Bibliographic Details
Main Authors: Jonathan Mapelli, Giulia Maria Boiani, Egidio D’Angelo, Albertino Bigiani, Daniela Gandolfi
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
gain modulation
long-term plasticity
cerebellum
granule cell
computational modeling
Online Access:https://www.mdpi.com/2227-9059/10/12/3185

Internet

https://www.mdpi.com/2227-9059/10/12/3185

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