<it>BIRC6 (APOLLON)</it> is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation

<it>BIRC6 (APOLLON)</it> is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation

<p>Abstract</p> <p>Background</p> <p>Inhibitors of apoptosis (IAPs) were intensively investigated in the context of cancer where they promote tumor growth and chemoresistence. Overexpression of the IAP <it>BIRC6</it> is associated with unfavorable clinical f...

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Bibliographic Details
Main Authors: Schläfli Anna M, Torbett Bruce E, Fey Martin F, Tschan Mario P
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Experimental Hematology & Oncology
Subjects:
<it>BIRC6</it>
Acute myeloid leukemia
Acute promyelocytic leukemia
ATRA
Neutrophil differentiation
Online Access:http://www.ehoonline.org/content/1/1/25

Internet

http://www.ehoonline.org/content/1/1/25

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