Synthesis and anticancer evaluation of 2-phenyl thiaolidinone substituted 2-phenyl benzothiazole-6-carboxylic acid derivatives

Synthesis and anticancer evaluation of 2-phenyl thiaolidinone substituted 2-phenyl benzothiazole-6-carboxylic acid derivatives

A novel series of 2-(3-(4-oxo-2-substituted phenyl thiazolidin-3-yl)phenyl)benzo[d]thiazole-6-carboxylic acid derivatives PP1–PP8 were synthesized by various benzothiazole Schiff’s bases by reaction with thioglycollic acid. Their structures were established on the basis of IR, 1H-NMR, 13C-NMR, mass...

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Bibliographic Details
Main Authors: Padmavathi P. Prabhu, T. Panneerselvam, C.S. Shastry, A. Sivakumar, Sushant S. Pande
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Journal of Saudi Chemical Society
Subjects:
Benzothiazole
Schiff bases
Thiazolidinones
Anticancer activity
HeLa cell lines
MTT assay
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610312000142

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http://www.sciencedirect.com/science/article/pii/S1319610312000142

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