Retinoic Acid Receptor Gamma (RARγ) Promotes Cartilage Destruction through Positive Feedback Activation of NF-κB Pathway in Human Osteoarthritis

Osteoarthritis (OA) is a severe inflammation-related disease which leads to cartilage destruction. The retinoic acid receptor gamma (RARγ) has been indicated to be involved in many inflammation processes. However, the role and mechanism of RARγ in cartilage destruction caused by inflammation in OA a...

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Bibliographic Details
Main Authors: Yue-Wei Yu, Si-Yang Li, Lin-Jun Zhang, Qian-Liang Wang, Zhong-Guo Liu, Qing-Zhi Chen, Hong-Yu Song, Dong-Yan Shen, Jun Yan
Format: Article
Language:English
Published: Hindawi Limited 2022-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2022/1875736