Inferring RNA sequence preferences for poorly studied RNA-binding proteins based on co-evolution

Abstract Background Characterizing the binding preference of RNA-binding proteins (RBP) is essential for us to understand the interaction between an RBP and its RNA targets, and to decipher the mechanism of post-transcriptional regulation. Experimental methods have been used to generate protein-RNA...

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Bibliographic Details
Main Authors: Shu Yang, Junwen Wang, Raymond T. Ng
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2091-8