Dysregulated NAD(H) homeostasis associated with ciprofloxacin tolerance in Escherichia coli investigated on a single-cell level with the Peredox [NADH:NAD+] biosensor

Dysregulated NAD(H) homeostasis associated with ciprofloxacin tolerance in Escherichia coli investigated on a single-cell level with the Peredox [NADH:NAD+] biosensor

IntroductionAntibiotic persistence (subpopulation tolerance) occurs when a subpopulation of antibiotic sensitive cells survives prolonged exposure to a bactericidal concentration of an antibiotic, and is capable of regrowth once the antibiotic is removed. This phenomenon has been shown to contribute...

Full description

Bibliographic Details
Main Authors: Joanna Urbaniec, Martina Sanderson-Smith, Johnjoe McFadden, Faisal I. Hai, Suzanne M. Hingley-Wilson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
tolerance
AMR
antibiotic
ciprofloxacin
NADH
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1191968/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1191968/full

Similar Items