A mycobacterium ESX-1-secreted virulence factor with unique requirements for export.

Specialized secretion systems of pathogenic bacteria commonly transport multiple effectors that act in concert to control and exploit the host cell as a replication-permissive niche. Both the Mycobacterium marinum and the Mycobacterium tuberculosis genomes contain an extended region of difference 1...

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Bibliographic Details
Main Authors: Bryant McLaughlin, Janet S Chon, Jason A MacGurn, Fredric Carlsson, Terri L Cheng, Jeffery S Cox, Eric J Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1937011?pdf=render