Effects of pentoxifylline on TNF-alpha and lung histopathology in HCL-induced lung injury

Effects of pentoxifylline on TNF-alpha and lung histopathology in HCL-induced lung injury

OBJECTIVE: To evaluate the effects of pentoxifylline on hydrochloric acid-induced lung lesions in rats subjected to mechanical ventilation. METHODS: Twenty male, adult Wistar-EPM-1 rats were anesthetized and randomly grouped (n=5 animals per group) as follows: control-MV (mechanical ventilation, MV...

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Bibliographic Details
Main Authors: Itamar Souza de Oliveira-Júnior, Carla Cristina Maganhin, Adriana Aparecida Ferraz Carbonel, Cristina Maria Rodrigues Monteiro, Sâmia Santos Cavassani, Ricardo Martins Oliveira-Filho
Format: Article
Language:English
Published: Elsevier España 2008-01-01
Series:Clinics
Subjects:
Acid aspiration
Acute lung injury
Mechanical ventilation
corticosterone
Cytokine
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322008000100014

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322008000100014

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