Ameliorative effects of Danshensu from the functional food Salvia miltiorrhiza against arsenic trioxide-induced cardiac toxicity in vivo and in vitro: Involvement of inhibiting the AKT/IKK/NF-κB signaling pathway

Ameliorative effects of Danshensu from the functional food Salvia miltiorrhiza against arsenic trioxide-induced cardiac toxicity in vivo and in vitro: Involvement of inhibiting the AKT/IKK/NF-κB signaling pathway

Cardiotoxicity is a serious side effect of arsenic trioxide (ATO) which hinders its clinical use in cancer chemotherapy. Danshensu (DSS) has potential applications in the food and healthcare industry to promote cardiovascular health. The experiment aims to investigate the effects of DSS against ATO-...

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Bibliographic Details
Main Authors: Yakun Yang, Jiaying Qi, Hua Wang, Yang Zhao, Yongchao Wu, Zhonglin Wu, Jing Shi, Weizhong Qu, Li Chu
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Functional Foods
Subjects:
Danshensu
Arsenic trioxide
Cardiotoxicity
Oxidative stress
AKT/IKK/NF-κB pathway
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622003747

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http://www.sciencedirect.com/science/article/pii/S1756464622003747

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