MiR-574-3p inhibits glucose toxicity-induced pancreatic β-cell dysfunction by suppressing PRMT1

MiR-574-3p inhibits glucose toxicity-induced pancreatic β-cell dysfunction by suppressing PRMT1

Abstract Background Pancreatic β-cell dysfunction is commonly observed in patients with type 2 diabetes mellitus. Protein arginine methyltransferase 1 (PRMT1) plays an important role in pancreatic β-cell dysfunction. However, the detailed mechanisms remain largely unknown. Methods RT-qPCR, western b...

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Bibliographic Details
Main Authors: Lixia Lv, Xiumin Wang, Jinhua Shen, Ying Cao, Qin Zhang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Diabetology & Metabolic Syndrome
Subjects:
miR-574-3p
PRMT1
Proliferation
Apoptosis
Insulin secretion
Online Access:https://doi.org/10.1186/s13098-022-00869-y

Internet

https://doi.org/10.1186/s13098-022-00869-y

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