SSBlazer: a genome-wide nucleotide-resolution model for predicting single-strand break sites

SSBlazer: a genome-wide nucleotide-resolution model for predicting single-strand break sites

Abstract Single-strand breaks are the major DNA damage in the genome and serve a crucial role in various biological processes. To reveal the significance of single-strand breaks, multiple sequencing-based single-strand break detection methods have been developed, which are costly and unfeasible for...

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Bibliographic Details
Main Authors: Sheng Xu, Junkang Wei, Siqi Sun, Jizhou Zhang, Ting-Fung Chan, Yu Li
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Genome Biology
Subjects:
Single-strand break
Genome instability
Nucleotide-resolution model
Online Access:https://doi.org/10.1186/s13059-024-03179-w

Internet

https://doi.org/10.1186/s13059-024-03179-w

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