Safety and Immunogenicity Analysis of a Newcastle Disease Virus (NDV-HXP-S) Expressing the Spike Protein of SARS-CoV-2 in Sprague Dawley Rats

Safety and Immunogenicity Analysis of a Newcastle Disease Virus (NDV-HXP-S) Expressing the Spike Protein of SARS-CoV-2 in Sprague Dawley Rats

Despite global vaccination efforts, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve and spread globally. Relatively high vaccination rates have been achieved in most regions of the United States and several countries worldwide. However, access to vaccines in low- and...

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Bibliographic Details
Main Authors: Johnstone Tcheou, Ariel Raskin, Gagandeep Singh, Hisaaki Kawabata, Dominika Bielak, Weina Sun, Irene González-Domínguez, D Noah Sather, Adolfo García-Sastre, Peter Palese, Florian Krammer, Juan Manuel Carreño
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
COVID-19
SARS-CoV-2
newcastle disease virus
vaccine
immunogenicity
safety
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.791764/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.791764/full

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