Biotin-decorated celastrol-loaded ZIF-8 nanoparticles induce ferroptosis for colorectal cancer therapy

Biotin-decorated celastrol-loaded ZIF-8 nanoparticles induce ferroptosis for colorectal cancer therapy

Celastrol (CEL) has garnered significant interest for its anti-tumour properties and potential for colorectal cancer (CRC) treatment. However, its clinical use is constrained by its limited bioavailability and potential toxicity. Herein, a biotin-decorated CEL nano-drug delivery system using a zeoli...

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Bibliographic Details
Main Authors: Jie Chen, Yan Liu, Yanting You, Ruisi Zhou, Yanchun Li, Xinghong Zhou, Xiaohu Chen, Ying Yang, Jinxiang Chen, Hiu Yee Kwan, Xiaoshan Zhao, Yuyao Wu
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Materials & Design
Subjects:
Celastrol
Colorectal cancer
Ferroptosis
Zeolitic imidazolate framework-8
Nano-drug
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127524001862

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http://www.sciencedirect.com/science/article/pii/S0264127524001862

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