Obg-Like ATPase 1 Enhances Chemoresistance of Breast Cancer via Activation of TGF-β/Smad Axis Cascades

Obg-Like ATPase 1 Enhances Chemoresistance of Breast Cancer via Activation of TGF-β/Smad Axis Cascades

Understanding the molecular mechanism of drug resistance helps to identify an effective target for breast cancer therapy. In this study we investigated the regulatory role of Obg-like ATPase 1 which is involved in multiple uses of drug resistance against breast cancer. Paclitaxel resistant cell line...

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Bibliographic Details
Main Authors: Jianzhou Liu, Xiaoyu Miao, Bowen Xiao, Jing Huang, Xufeng Tao, Jiong Zhang, Hua Zhao, Yue Pan, Hongwei Wang, Ge Gao, Gary Guishan Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
Obg-like ATPase 1
breast cancer
chemosensitivity
γ-tubulin
multidrug resistance
paclitaxel
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00666/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00666/full

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