Layer-specific stem cell differentiation in tri-layered tissue engineering biomaterials: Towards development of a single-stage cell-based approach for osteochondral defect repair

Successful repair of osteochondral defects is challenging, due in part to their complex gradient nature. Tissue engineering approaches have shown promise with the development of layered scaffolds that aim to promote cartilage and bone regeneration within the defect. The clinical potential of implant...

Full description

Bibliographic Details
Main Authors: Tanya J. Levingstone, Conor Moran, Henrique V. Almeida, Daniel J. Kelly, Fergal J. O'Brien
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006421000818