Proteomic profiling of formalin-fixed paraffine-embedded tissue reveals key proteins related to lung dysfunction in idiopathic pulmonary fibrosis

Proteomic profiling of formalin-fixed paraffine-embedded tissue reveals key proteins related to lung dysfunction in idiopathic pulmonary fibrosis

IntroductionIdiopathic pulmonary fibrosis (IPF) severely affects the lung leading to aberrant deposition of extracellular matrix and parenchymal stiffness with progressive functional derangement. The limited availability of fresh tissues represents one of the major limitations to study the molecular...

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Main Authors: Anna Valeria Samarelli, Roberto Tonelli, Giulia Raineri, Giulia Bruzzi, Dario Andrisani, Filippo Gozzi, Alessandro Marchioni, Matteo Costantini, Luca Fabbiani, Filippo Genovese, Diego Pinetti, Linda Manicardi, Ivana Castaniere, Valentina Masciale, Beatrice Aramini, Luca Tabbì, Simone Rizzato, Stefania Bettelli, Samantha Manfredini, Massimo Dominici, Enrico Clini, Stefania Cerri
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Oncology
Subjects:
pulmonary fibrosis
mass spectrometry
molecular profiling
lung function decline
rare disease
IPF
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1275346/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1275346/full

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