LCAT1 is an oncogenic LncRNA by stabilizing the IGF2BP2-CDC6 axis

Abstract Long non-coding RNAs (lncRNAs) is known to play vital roles in modulating tumorigenesis. We previously reported that LCAT1, a novel lncRNA, promotes the growth and metastasis of lung cancer cells both in vitro and in vivo. However, the underlying mechanism(s) of LCAT1 as an oncogenic regula...

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Bibliographic Details
Main Authors: Juze Yang, Xinyi Qian, Qiongzi Qiu, Lingling Xu, Meidie Pan, Jia Li, Jiayi Ren, Bingjian Lu, Ting Qiu, Enguo Chen, Kejing Ying, Honghe Zhang, Yan Lu, Pengyuan Liu
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05316-4