TGF-β1-overexpressing mesenchymal stem cells reciprocally regulate Th17/Treg cells by regulating the expression of IFN-γ

TGF-β1-overexpressing mesenchymal stem cells reciprocally regulate Th17/Treg cells by regulating the expression of IFN-γ

Transforming growth factor (TGF)-β1 and mesenchymal stromal cells (MSCs) are two effective immunosuppressive agents for organ transplantation technology. This study aims to explore the molecular mechanism of TGF-β1-overexpressed MSCs on T cell immunosuppression. To achieve that, BM-MSCs were isolate...

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Bibliographic Details
Main Authors: Li Ruixue, Wang Renyong, Zhong Shijie, Asghar Farhan, Li Tiehan, Zhu Lei, Zhu Hong
Format: Article
Language:English
Published: De Gruyter 2021-11-01
Series:Open Life Sciences
Subjects:
tgf-β1
msc
th17
treg
immunosuppression
Online Access:https://doi.org/10.1515/biol-2021-0118

Internet

https://doi.org/10.1515/biol-2021-0118

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