Interaction of genetic variants and methylation in transcript-level expression regulation in Alzheimer’s disease by multi-omics data analysis

Interaction of genetic variants and methylation in transcript-level expression regulation in Alzheimer’s disease by multi-omics data analysis

Abstract Background Alzheimer’s disease (AD) presents a significant public health problem and major cause of dementia. Not only genetic but epigenetic factors contribute to complex and heterogeneous molecular mechanisms underlying AD risk; in particular, single nucleotide polymorphisms (SNPs) and DN...

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Bibliografische gegevens
Hoofdauteurs: Seonggyun Han, Soo-ah Cho, Wongyung Choi, Karen Eilbeck, Hilary Coon, Kwangsik Nho, Younghee Lee
Formaat: Artikel
Taal:English
Gepubliceerd in: BMC 2025-02-01
Reeks:BMC Genomics
Onderwerpen:
Alzheimer’s disease
SNP
Methylation
Genetic regulation
Epigenetic regulation
Online toegang:https://doi.org/10.1186/s12864-025-11362-x

Internet

https://doi.org/10.1186/s12864-025-11362-x

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